Motion Apparent Diffusion in Biological Systems

This work describes the basics of diffusion measurement in biological systems. The first portion is dedicated to providing an understandable, classical-mechanical description of the Stejskal ] Tanner pulse sequence to give the reader an intuitive understanding of the measurement. This is followed by a description of the various aspects of water motion in biological systems that should be taken into account when making and ( ) interpreting apparent diffusion coefficient ADC measurements. These include free diffusion, restricted diffusion, diffusion anisotropy, population weighting, and the difference ( ) between diffusion-weighted imaging DWI and ADC maps. Q 1997 John Wiley & Sons, Inc. Concepts Magn Reson 9: 385 ] 401, 1997